đź“ś The Toddler Scroll of Drug Reactions
“How some medicines can make Bodyland’s brain, kidneys, lungs, and whole body act differently!”
🧠Nervous System Reactions
- Cinchonism: Caused by Quinidine, Quinine.
Causes ringing in ears (tinnitus), hearing/vision loss, and confusion (psychosis). - Parkinson-like syndrome: Caused by Antipsychotics, Reserpine, Metoclopramide.
Causes stiff and shaky arms (cogwheel rigidity of ARM). - Peripheral neuropathy: Caused by Isoniazid, Phenytoin, Platinum agents, Vincristine.
Numbness and weakness in hands and feet. - Idiopathic intracranial hypertension: Caused by Growth hormones, Tetracyclines, Vitamin A.
High pressure in the head causing headaches. - Seizures: Caused by Isoniazid, Bupropion, Imipenem/cilastatin, Tramadol, Enflurane.
Mnemonic: With seizures, I BITE my tongue. - Tardive dyskinesia: Caused by Antipsychotics, Metoclopramide.
Involuntary movements. - Visual disturbance: Caused by Topiramate, Digoxin, Isoniazid, Vigabatrin, PDE-5 inhibitors, Ethambutol.
Mnemonic: These Drugs Irritate Very Precious Eyes.
đź©ş Renal/Genitourinary Reactions
- Fanconi syndrome: Caused by Cisplatin, Ifosfamide, expired tetracyclines, Tenofovir.
- Hemorrhagic cystitis: Caused by Cyclophosphamide, Ifosfamide.
Can be prevented by giving mesna. - Interstitial nephritis: Caused by Diuretics (Pee), NSAIDs (Pain-free), Penicillins, Cephalosporins, PPIs, Rifampin, Sulfa drugs.
Mnemonic: Remember the 5 P’s.
🌬️ Respiratory Reactions
- Dry cough: Caused by ACE inhibitors.
- Pulmonary fibrosis: Caused by Methotrexate, Nitrofurantoin, Carmustine, Bleomycin, Busulfan, Amiodarone.
Mnemonic: My Nose Cannot Breathe Bad Air.
🌍 Multiorgan Reactions
- Antimuscarinic effects: Caused by Atropine, TCAs, H1 blockers, Antipsychotics.
- Disulfiram-like reaction: Caused by 1st generation Sulfonylureas, Procarbazine, Cephalosporins, Griseofulvin, Metronidazole.
Mnemonic: Sorry Pals, Can’t Go Mingle. - Nephrotoxicity/ototoxicity: Caused by Loop diuretics, Aminoglycosides, Cisplatin, Vancomycin, Amphotericin B.
Mnemonic: Listen And Pee Very TERRiBly.
Medicines can sometimes cause many different reactions, but knowing these helps Bodyland stay safe and happy!